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It is currently the main packaging method for solid dosage forms such as pharmaceutical tablets and capsules
Pharmaceutical aluminum-plastic blister packaging has been widely used in the pharmaceutical industry due to its beautiful appearance, good barrier properties, ease of use, and portability. It is currently the main packaging method for solid dosage forms such as pharmaceutical tablets and capsules. one.
Pharmaceutical packaging aluminum foil (usually called PTP aluminum foil) is one of the two major constituent materials of this packaging method, and its pinhole degree will directly affect the protection of the final packaging to the contents. Because if the PTP aluminum foil pinhole is just in the blister, it means that the medicine is in direct contact with the outside air, and the protective function of the medicine packaging will be completely lost, which will bring great risks to the manufacturers and users of the medicine. This risk is unacceptable for most drug manufacturers.
There are two reasons for pinholes in PTP aluminum foil: ①pinholes in the production process of the raw material used in the production of PTP aluminum foil; ②pinholes in the production process of PTP aluminum foil. Because the pinholes in the PTP aluminum foil production process are relatively easy to control and avoid, the following discussion mainly focuses on the pinholes generated in the production process of the raw material aluminum foil for PTP aluminum foil (hereinafter referred to as the raw aluminum foil).