It is currently the primary packaging method for solid dosage forms such as tablets and capsules. 2022-06-29

Release date:

2022-12-14

Pharmaceutical aluminum-plastic blister packaging, with its attractive appearance, excellent barrier properties, ease of use, and portability, has found widespread application in the pharmaceutical industry and is now one of the primary packaging formats for solid dosage forms such as tablets and capsules.

Pharmaceutical packaging aluminum foil—commonly referred to as PTP aluminum foil—is one of the two primary components of this packaging system, and its pinhole density directly affects the final package’s ability to protect the product. If a pinhole in the PTP foil aligns with the blister cavity, it results in direct contact between the drug and the external atmosphere, completely compromising the protective function of the packaging and posing significant risks to both manufacturers and users. Such risks are unacceptable to most pharmaceutical manufacturers.

There are two causes of pinholes in PTP aluminum foil: (1) pinholes that arise during the production of the raw materials used to manufacture PTP aluminum foil, and (2) pinholes that occur during the PTP aluminum foil manufacturing process itself. Since pinholes originating in the production process are relatively easy to control and prevent, this discussion will focus primarily on those arising during the fabrication of the base aluminum foil—hereafter referred to as “base aluminum foil.”

It is currently the primary packaging method for solid dosage forms such as tablets and capsules.