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What are the commonly used pharmaceutical packaging materials
What are the commonly used pharmaceutical packaging materials? I believe many friends would like to know. Here, I have edited and sorted out the relevant content about the commonly used pharmaceutical packaging materials, hoping to be helpful to everyone.
① Glass: Glass has the advantages of moisture-proof, easy sealing, transparency and relatively stable chemical properties, but glass also has many shortcomings, such as heavier and fragile, and can also release alkaline substances and insoluble tablets due to erosion by aqueous solutions. In order to ensure the quality of medicines, the Pharmacopoeia stipulates that ampoules and large infusion bottles must use hard neutral glass, and containers made of brown glass should be used when containing medicines that are easily deteriorated in case of light.
② Plastic: Plastic has the advantages of firm packaging, easy sealing, bright color, transparent and beautiful, light weight, convenient carrying, and low price. However, due to the fact that additives, such as plasticizers and stabilizers, are often added to plastics in production, these additives may be in direct contact with drugs. Chemical reactions occur with drugs, resulting in changes in drug quality. Plastics also have shortcomings such as air and light transmission, and easy adsorption. These shortcomings can accelerate the rate of oxidative deterioration of drugs and cause drug deterioration.
③ Paper products: Paper products have a wide range of sources, low cost, and have a certain moisture-proof performance after being brushed with moisture-proof paint. The packaging volume can be manufactured as needed, and it has the value of recycling. It is one of the most widely used packaging materials today. Disadvantages: low strength and easy deformation.
④ Metal: commonly used are black iron sheet, galvanized iron sheet, tinplate, aluminum foil, etc. This type of packaging has good pressure resistance, sealing and performance, but the cost is relatively high.
Wood: With pressure resistance, it is a commonly used outer packaging material. Due to the consumption of forest resources, it is gradually replaced by materials such as paper and plastic.
Composite material: Composite material is a rookie among packaging materials. It is a packaging material made of multi-layer composite of plastic, paper, aluminum foil, etc. Commonly used are paper-plastic composite material, aluminum foil-polyethylene composite material, aluminum foil-polyester ethylene, etc. These composite materials have good mechanical strength, biological corrosion resistance, vacuum maintenance performance and compressive performance.
Rubber products: mainly used for various bottle stoppers of bottled medicines, due to direct contact with medicines, it is required to have very good biochemical stability and excellent sealing to ensure that the entry of air and moisture is not deteriorated within the valid period.
From the perspective of development trends, packaging materials are developing in the direction of replacing wood with paper, replacing paper with plastic, or forming various composite materials with paper, plastic, and aluminum foil. Applications such as special packaging materials such as PTFE, silicone resins, polyester composite panels or foamed polyurethane are on the rise.